- Stock: 1
- Model: Dihexa
- SKU: C27H44N4O5
Certificate of analysis
Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, or its developmental code name PNB-0408, is an oligopeptide drug derived from angiotensin IV. It binds with high affinity to hepatocyte growth factor (HGF) and interacts with its receptor, c-Met.
The molecular formula of Dihexa is C27H44N4O5, with a molar mass of 504.672 g·mol−1.
Dihexa consists of two hydrophobic amino acids—Tyr-Ile—with the full sequence as follows: Hexanoyl-Tyr-Ile-Ahx-NH2.
Solubility Information
Important: Due to its hydrophobic nature, Dihexa does not dissolve in pure water and must be mixed with a suitable solvent such as DMSO. This is essential for proper reconstitution.
Based on laboratory testing and published research:
- Dihexa dissolves well in DMSO at a concentration of 1mg/ml.
- Adding 1ml of pure water may cause the solution to become cloudy.
- Applying ultrasonic treatment for 2 seconds typically clears the solution.
This solubility profile is also why Dihexa is more commonly offered in capsule form. Researchers intending to work with the lyophilised version should ensure access to DMSO or a similar solvent for proper handling.
Storage Guidelines
Store the lyophilised peptide at -20°C. Once reconstituted, use it immediately or store it at 2–8°C for a short duration. Avoid repeated freeze-thaw cycles.
Disclaimer: This product is intended for laboratory research use only. It is not approved for human or veterinary use.
| Identification | |
| Molecular Weight (g/mol) | 504.66 g/mol |
| Peptide Sequence | N-hexanoic-Tyr-Ile-(6)aminohexanoic amide |
| CAS Number | 1401708-83-5 |
| Physical and Chemical Properties | |
| Molecular Formula | C27H44N4O5 |
| Appearance | White to off-white lyophilised powder |
| Melting Point | Not applicable (decomposes before melting) |
| Research Use and Safety | |
| Caution | Handle using appropriate PPE and in compliance with relevant laboratory safety standards. |
| Intended Use | For laboratory research use only. Not for human or veterinary use. |
| Hazard Classification | Not classified as hazardous under GHS for research quantities |
| Storage, Handling and Stability | |
| Storage Temperature, Opened | -20 °C, minimise freeze-thaw cycles |
| Storage Temperature, Unopened | -20 °C recommended for long-term storage |
| Shelf Life | 2 years unopened under recommended conditions |
| Reconstitution Stability | Stable for up to 28 days at 2-8 °C in aqueous solution under sterile conditions |